The effect of sodium monofluoroacetate on plasma testosterone concentration in Tiliqua rugosa (Gray).
Document Type
Article
Publication Date
8-17-1987
Journal Title
Comparative biochemistry and physiology
Keywords
Tiliqua rugosa, Sodium monofluoroacetate, Plasma testosterone
Abstract
Administration of multiple or single doses of sodium fluoroacetate (1080) to male Tiliqua rugosa caused a decrease in plasma testosterone concentration.
A single dose of 100 or 250 mg 1080 kg body weight decreased plasma testosterone by 52%. However, 25 mg kg had a little apparent effect on testosterone levels. When lizards are given the multiple doses equivalent of those doses of over 12 days at 3 day intervals, the effect was much less dramatic with plasma testosterone concentration steadily declining over 15 days for the two higher doses.
There was a suggestion of degeneration of seminiferous tubules in some individuals.
Recommended Citation
Twigg, L E, King, D R, and Bradley, A J. (1987), The effect of sodium monofluoroacetate on plasma testosterone concentration in Tiliqua rugosa (Gray).. Comparative biochemistry and physiology, Vol. 91C (No. 2), 343-347.
