Relationships between fibre intake and the expression of genes linked to incretin secretion in the gastrointestinal tract of weaner pigs
Document Type
Conference Proceeding
Publication Date
11-2013
Conference Title
Fourteenth Biennial Conference of the Australasian Pig Science Association
Place of Publication
Melbourne
ISBN
978-0-9806880-3-0
ISSN
1324 9177
Keywords
pigs, swine, pork, fibre intake, diet
Disciplines
Meat Science | Other Animal Sciences
Abstract
Dietary fibre [predominately non-starch polysaccharides (NSP) and resistant starch] is fermented to short chain fatty acids (SCFA) by the microbiota in the distal gastrointestinal tract (GIT). The activation of G-protein coupled receptors (GPRs), such as GPR41 and GPR43, by SCFA in the epithelium activates the proglucagon (PG) gene in the L cells of the GIT to secrete incretins such as glucagon-like peptides (GLP-1, GLP-2) and peptide YY (PYY), that in turn are implicated in the control of GIT structure and function (Black et al., 2009). We are unaware of any work conducted in weaner pigs in this area. The hypothesis tested was that the expression of genes coding for GPRs and PG is influenced by the intake of NSP.
Recommended Citation
Pluske, J R,
Hernandez, A,
Mansfield, J,
Auckland, C H,
and
Kim, J C.
(2013), Relationships between fibre intake and the expression of genes linked to incretin secretion in the gastrointestinal tract of weaner pigs, Fourteenth Biennial Conference of the Australasian Pig Science Association, Melbourne, pp.116-116.
https://library.dpird.wa.gov.au/conf_papers/232
