Combined supplementation of boron, vitamin E and omega-3 fatty acids increases tight junction protein mRNA expression in the colon of E. coli-infected weaner pigs

Authors

J C. Kim, Department of Agriculture and Food, WAFollow
Karen L. Moore, Department of Agriculture and Food Western AustraliaFollow
M Trezona, Department of Agriculture and Food WA
M D. Langridge, Department of Agriculture and Food, WA
Bruce P. Mullan, Department of Primary Industries and Regional Development, Western AustraliaFollow
John R. Pluske, Murdoch UniversityFollow

Document Type

Article

Publication Date

11-11-2015

Journal Title

Animal Production Science

ISSN

Print: 1836-0939 Electronic: 1836-5787

Keywords

E. coli, weaner pigs, pigs, swine

Disciplines

Meat Science | Other Animal Sciences

Abstract

Enhancing intestinal barrier function and protection against epithelial cell damage in weaner pigs challenged by bacterial and (or) environmental stressors can improve health and growth efficiency. Among many nutrients boron (B), vitamin E (VE) and omega-3 fatty acids (n-3 FA) are known to reduce bacterial infection-induced responses through regulation of eicosanoid mediators and improved antioxidant capacity (Kim et al. 2013). This study tested the hypothesis that dietary supplementation with a combination of B, VE and n-3 FA will improve intestinal barrier function in weaned pigs infected with an enterotoxigenic strain of E. coli through down regulation of eicosanoid mediators and improved antioxidant capacity.

Recommended Citation

Kim, J C, Moore, K L, Trezona, M, Langridge, M D, Mullan, B P, and Pluske, J R. (2015), Combined supplementation of boron, vitamin E and omega-3 fatty acids increases tight junction protein mRNA expression in the colon of E. coli-infected weaner pigs. Animal Production Science, 55 (12), 1542-1542.
https://library.dpird.wa.gov.au/ap_researchart/31