Title

The effect of sodium monofluoroacetate on plasma testosterone concentration in Tiliqua rugosa (Gray).

Authors

L. E. Twigg
D. R. King
A. J. Bradley

Document Type

Article

Publication Date

8-17-1987

Journal Title

Comparative biochemistry and physiology

Keywords

Tiliqua rugosa, Sodium monofluoroacetate, Plasma testosterone

Abstract

Administration of multiple or single doses of sodium fluoroacetate (1080) to male Tiliqua rugosa caused a decrease in plasma testosterone concentration.

A single dose of 100 or 250 mg 1080 kg body weight decreased plasma testosterone by 52%. However, 25 mg kg had a little apparent effect on testosterone levels. When lizards are given the multiple doses equivalent of those doses of over 12 days at 3 day intervals, the effect was much less dramatic with plasma testosterone concentration steadily declining over 15 days for the two higher doses.

There was a suggestion of degeneration of seminiferous tubules in some individuals.

Recommended Citation

Twigg, L E, King, D R, and Bradley, A J. (1987), The effect of sodium monofluoroacetate on plasma testosterone concentration in Tiliqua rugosa (Gray).. Comparative biochemistry and physiology, Vol. 91C (No. 2), 343-347.